New Approved Treatment for Dupuytren's

I did a blog on Dupuytren's contracture last year that got a lot of interest. There are a lot of men out there with this condition and, apparently, many of them are reading EverythingHealth. I mentioned a new biologic drug that was being developed as a non-surgical treatment for Dupuytrens. At that time, it was still in testing phase and not available for use.

The product, collengenase clostridium histolyticum (Xiaflex) has now been approved and will be marketed by Auxilium Pharmaceuticas, Inc. It is injected directly into the palpable Dupuytren's cord, followed by a finger extension procedure 24 hours later to help distrupt the contracture cord.

The company plans to market Xiaflex to physicians experienced in hand injection procedures. The most common adverse reactions were fluid buildup, swelling, bleeding and pain in the injected area. No serious allergic reactions have been reported.


M.scott said…
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Stefano said…
I think that the better treatment will be a combination of needle-aponeurothomy ( - for the relaxing of the cords and the drug injection to treat the nodules.
No invasive surgery will be necessary.
If only my mother lived in the USA to receive this new treatment. She has had 2 ops on both her hand for Dupuytren's. Unfortunately this has not cured it for her and a 3rd op in the near future looks like it will happen.
link wheel said…
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linkwheel said…
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so dep said…
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In February 2011, the European Commission's Committee for Medicinal Products for Human Use licensed Pfizer's Xiapex product, a 0.9 mg powder-and-solvent injectable collagenase clostridium histolyticum kit for the treatment by 'properly trained' doctors of Dupuytren's contracture in adults with a palpable cord, who are not 'allergic to the active substance or any of the other ingredients'.
viagra said…
The treatment is so nasty but it actually works incredible for me, very recommendable for people who suffers this disease.

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