Sunday, May 2, 2010
Your Genes Determine Which Diet Works
(A single nucleotide polymorphism is a DNA sequence variation that can create a copying error for proteins that change how a gene works and can be the site of certain disease processes)
Dr. Nelson studied women on 4 popular weight loss diets. (Atkins, Zone, Learn and Ornish) Within each of the diet groups, there were women who had lost over 15kg as well as people who gained 5 kg. These women had no statistically significant differences in body mass index, blood pressure, cholesterol levels, insulin or glucose. The only difference was the genotype.
Remember, that everyone loses weight when you limit calories. But how you get those calories seems to make a difference in how much weight you lose over time. Some of us are low-carb losers and some are low-fat losers. At this time there is no way to know which one you may be if you don't know your genotype. Will this be the wave of the future?
Dr. Nelson acknowledged that the trial was relatively small and that the findings need to be confirmed in a larger trial. For now if you aren't seeing your weight loss with one type of diet, it might be time to switch to another.
Posted by Toni Brayer, MD at 9:07 AM